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Preimplantation diagnosis (PGD) of IVF

What is Preimplantation Diagnosis (PGD)?

Preimplantation Diagnosis (PGD) is the only clinically valid genetic screening test based on massive next generation sequencing. It is the most comprehensive and accurate test available.

PGD is an option for couples whose offspring are at high risk of developing a serious hereditary disease.

Preimplantation genetic diagnosis (PGD) is a genetic examination of the embryo before (pre-) implantation in the uterus. For this purpose, certain cells are removed from the embryo approximately five days after fertilization and genetically examined. The removal of these cells does not usually harm the embryo. Embryos that are unaffected by the genetic change being studied are then selected for transfer to the woman’s uterus.

Even if there is no fertility problem, artificial insemination (IVF/ICSI) is still required for PGD in order to examine the embryos in the laboratory.

Diagnostic preimplantatoire de FIV en Tunisie

Why have a Preimplantation Diagnosis (PGD)?

Usually, parents become aware after the birth of a sick child that they are carrying one or more serious genetic diseases. Genetic diseases can be prevented, but they cannot be cured. This is the only clinically valid test.

Who is Preimplantation Diagnosis (PGD) for?

All people have genetic changes, and Preimplantation Diagnosis allows us to know if this can cause diseases in our children.

The test is recommended in the following cases:

Before getting pregnant naturally
This is for any woman who wants to know before she gets pregnant if she is at risk of passing on any diseases to her children.
Before using assisted reproductive technologies (including artificial insemination)
it is advisable to identify the potential risks of disease transmission so that the best treatments for each case can be identified.
Before treatment with donor sperm or eggs
To select a donor who does not carry the same mutations as a person who needs donor cells.
PGD provides the family with information at the time of planning the pregnancy about risks that may occur during the pregnancy and for which additional embryo/fetal monitoring is required. The test provides information about the need for amniocentesis or chorionic biopsy during pregnancy to exclude possible single gene disorders.

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Les Berges du Lac, Tunis 1053, Tunisie

+ 33 (0)1 87 64 13 99

+44 (0) 20 38 85 06 59

+1 438-797-0207


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